A Cocktail of Dementia Research

Treatment for Alzheimer’s disease has been approved in some countries, however some patients experience side effects including swelling and small bleeds in the brain. We are using a condition known as Cerebral Amyloid Angiopathy-related inflammation as a model to better understand what cells are involved in the immune response occurring after treatment. The cell types, severity, and location of the immune response were compared between cases and controls using specific staining known as immunohistochemistry, which highlights different types of cells.

Around the world, millions of people suffer from neurodegenerative diseases such as Alzheimer’s or ALS. These maladies devastate patients and carers alike, putting a massive strain on healthcare systems. Scientists are racing against time to learn about these diseases and uncover new treatments that could change lives. Every bit of help matters and, sometimes, the tiniest helpers make the biggest impact. Enter the humble fruit fly, an unexpected yet incredible research sidekick. But how can studying such a tiny insect teach us so much about ourselves? Are we really that alike? Can we test groundbreaking medicines using flies? Come aboard and we’ll take flight!

Daniel Adenisimi is a medical doctor and a post-graduate researcher at the School of Biological Science (SOBS), whose research is focused on changing the way we detect Alzheimer’s Disease (AD). His work aims to diagnose AD early, predict progression, and personalize treatment with a simple blood test. Dr. Daniel believes his project is not just about science; it’s about hope, innovation, and the future of AD diagnosis. By combining cutting-edge science with artificial intelligence, a world where Alzheimer’s Disease is no longer devastating but a highly manageable condition is possible.